Selective electrochemical oxidation of aromatic hydrocarbons and preparation of mono/multi-carbonyl compounds

摘要

A selective electrochemical oxidation was developed under mild condition.Various mono-carbonyl and multi-carbonyl compounds can be prepared from different aromatic hydrocarbons with moderate to excellent yield and selectivity by virtue of this electrochemical oxidation.The produced carbonyl compounds can be further transformed intoα-ketoamides,homoallylic alcohols and oximes in a one-pot reaction.In particular,a series ofα-ketoamides were prepared in a one-pot continuous electrolysis.Mechanistic studies showed that 2,2,2-trifluoroethan-1-ol(TFE)can interact with catalyst species and generate the corresponding hydrogen-bonding complex to enhance the electrochemical oxidation performance.