Key Laboratory for Developmental Genes and Human Disease Ministry of Education Institute of Life Sciences Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research Southeast University Nanjing 210096 ChinaMOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute Zhejiang University Hangzhou 310058 China;
MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute Zhejiang University Hangzhou 310058 ChinaSir Run Run Shaw Hospital College of Medicine Zhejiang University Hangzhou 310016 China;
Key Laboratory for Developmental Genes and Human Disease Ministry of Education Institute of Life Sciences Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research Southeast University Nanjing 210096 ChinaMOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute Zhejiang University Hangzhou 310058 China;
IRFs; ubiquitination; E3 ubiquitin ligase; viral proteins; activation; degradation;