目的 旨在探讨脑星形细胞瘤近瘤周、远瘤周白质区的扩散张量成像(DTI)特征.方法 37例脑星形细胞瘤术前行DTI扫描,其中Ⅰ级6例,Ⅱ级12例,Ⅲ级10例,Ⅳ级9例.重建FA图和FA编码彩色图,评价FA图像中近瘤周(IPR)白质、远瘤周 (DPR)白质及对侧正常脑白质区的信号特点,并测定相应平均称散率(MD)值及各向异性分数(FA)值.结果 Ⅳ级星形细胞瘤IPR白质的MD值高于其他三组(P<0.05),Ⅲ级星形细胞瘤IPR白质的FA值低于Ⅰ、Ⅱ级星形细胞瘤组(P<0.05).Ⅳ级星形细胞瘤IPR、DPR的白质FA值低于Ⅰ、Ⅱ、Ⅲ级星形细胞瘤组(P<0.05).结论 DTI能够较为直观的、准确地反映IPR及DPR白质区受肿瘤侵犯的情况.%Objective To investigate the DTI features of white matters at immediate and distance peritumoral regions in brain astrocytoma. Methods 37 patients with brain astrocytoma received pre-surgical DTI scanning. A-mong them, there were 6 cases of gradeⅠ , 12 of grade Ⅱ, 10 of grade Ⅲ and 9 of grade Ⅳ tumor. FA maps and color-coded FA maps were reconstructed. White matters at immediate peritumoral region (IPR), distance peritumoral region (DPR) and normal contralateral regions were evaluated for signal features and measured for MD and FA values. Results The IPR MD value of grade Ⅳ astrocytoma was remarkably higher than those of tumor with other 3 grades (P< 0.05); the IPR FA value of grade Ⅲ astrocytoma was lower that those of grades Ⅰ and Ⅱ tumors (P<0.05); and the IPR and DPR FA values of grade Ⅳ astrocytoma were significantly lower than those of grades Ⅰ , Ⅱ and Ⅲ tumors (P<0.05). Conclusion DTI provides intuitive and accurate visualization of tumor invasion at IPR and DPR.
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