Functional phenotyping of microglia highlights the dark relationship between chronic traumatic brain injury and normal age-related pathology

摘要

Traumatic brain injury(TBI)is a major cause of death and disability worldwide.Age-related TBI differences demonstrate the third peak of prevalence and incidence of TBI within the elderly population.This is due to the elderly being at a higher risk of sustaining falls,which have been identified as the main cause(40–50%)of TBI.