首页> 外文期刊>中国医学科学杂志:英文版 >ESTABLISHMENT OF A HUMAN T-LYMPHOMA CELL LINE(H-TL90) AND ANALYSIS OF ITS BIOLOGICAL CHARACTERISTICS
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ESTABLISHMENT OF A HUMAN T-LYMPHOMA CELL LINE(H-TL90) AND ANALYSIS OF ITS BIOLOGICAL CHARACTERISTICS

机译:人T淋巴瘤细胞系(H-TL90)的建立及其生物学特性分析

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ESTABLISHMENTOFAHUMANT-LYMPHOMACELLLINE(H-TL90)ANDANALYSISOFITSBIOLOGICALCHARACTERISTICSShiLi(史历),LiuXu(刘旭),ZhangYuemei(张月梅)L...
机译:We established a human T-lymphoma cell line from the cancerous ascites of a male patient with prostate cancer which was named H-TL90. This cell line was characterized by its histological features, and by chromosomal and immunological analysis. Immunophenotypic analysis revealed that the cells expressed surface antigen CD3- CD4- CD7+ CD8-. Biological analysis revealed that the cell can promote lymphocyte proliferation. This suggested that the cell line has an autosecretion function. Cytogenetic analysis revealed that H-TL90 was a hyperdlploid with 47 chromosomes and had characteristic translocation between chromosome 3 and 11, and the deletion of the long arm of chromosome 6. These results demonstrated the H-TL90 cell line can be a useful modal for the study of human T-lymphoma.

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