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Effect of Autophagy Over Liver Diseases

机译:自噬对肝脏疾病的影响

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摘要

Abstract In recent years, increasingly evidences show that autophagy plays an important role in the pathogenesis and development of liver diseases, and the relationship between them has increasingly become a focus of concern. Autophagy refers to the process through which the impaired organelles, misfolded protein, and intruding microorganisms is degraded by lysosomes to maintain stability inside cells. This article states the effect of autophagy on liver diseases (hepatic fibrosis, fatty liver, viral hepatitis, and liver cancer), which aims to provide a new direction for the treatment of liver diseases.
机译:摘要近年来,越来越多的证据表明自噬在肝病的发病和发展中起着重要作用,它们之间的关系越来越成为人们关注的焦点。自噬是指通过溶酶体降解受损细胞器,错误折叠的蛋白质和侵入性微生物以维持细胞内部稳定性的过程。本文阐述了自噬对肝脏疾病(肝纤维化,脂肪肝,病毒性肝炎和肝癌)的影响,旨在为肝脏疾病的治疗提供新的方向。

著录项

  • 来源
    《中国医学科学杂志(英文版)》 |2016年第1期|65-68|共4页
  • 作者单位

    Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;

    Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;

    Department of Pathology, Hunan University of Chinese Medicine, Changsha 410208, China;

    Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;

    Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;

    Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;

    Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;

  • 收录信息 中国科学引文数据库(CSCD);中国科技论文与引文数据库(CSTPCD);
  • 原文格式 PDF
  • 正文语种 eng
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