妊娠合并骨髓异常增生综合征1例

摘要

Myelodysplastic syndrome ( MDS) is a group heterogeneous of clonal myeloid disorders derived from hematopoietic stem cells . The pathological manifestations are abnormalities of myeloid cell differentiation and development .The clinical manifestations are ineffective hematopoiesis, refractory cytopenia, hematopoiesis failure and high-risk conversion to acute myeloid leukemia (AML).The treatment of MDS mainly focuses on two points: bone marrow failure and complications as well as AML transformation .For different patients , the natural disease course and prognosis of MDS varies widely and the treatment should be individualized .%骨髓增生异常综合征（ MDS）是起源于造血干细胞的一组异质性髓系克隆性疾病，病理学表现为髓系细胞分化及发育异常，临床表现为无效造血、难治性血细胞减少、造血功能衰竭，高风险向急性髓系白血病（ AML）转化。 MDS治疗主要集中于两类问题：骨髓衰竭及并发症、AML转化。对于不同的患者而言，MDS患者自然病程和预后的差异性很大，治疗宜个体化。