目的 了解上海市儿童医院手足口病后甲剥脱的流行病学特征,为手足口病后甲剥脱的监测和预控制提供科学依据.方法 回顾性研究上海市儿童医院2015年10月至2016年10月一年期间手足口病专病门诊就诊的手足口病患者和皮肤科门诊就诊的甲剥脱患者,分析其关联性、发病间隔时间、临床表现等因素.结果 6897例手足口病患者中148例出现甲剥脱,发病率为2.15%,男女比例1.31:1,平均发病年龄2.52±0.91岁.手足口病至甲剥脱间隔时间71.28±62.69天.148例患者临床均表现为双手和/或双足部分或全部指(趾)甲板从甲根部分离,发病时间较短者仅表现为少数指(趾)甲的甲根部横行带状变黄褪色或空鼓区域,随着时间的推后,部分患者出现近端甲板与甲跟部分离,甚至出现脱落和剥脱.结论 本研究认为手足口病后甲剥脱可作为手足口病的远期后遗症.%Objective To understand the epidemiological characteristics of onychomadesis after hand-foot-and-mouth-disease (HFMD)and to provide scientific basis for monitoring,preventing and controlling onychomadesis after HFMD.Methods Clinical data of HFMD patients visiting outpatient department specialized for HFMD and onychomadesis patients visiting dermatology outpatient department of Shanghai Children's Hospital from October 2015 to October 2016 were retrospectively studied.Their relevance,onset interval and clinical manifestation were analyzed.Results There were 148 cases with onychomadesis in 6 897 cases of HFMD,whose morbidity was 2.15%.Ratio of male to female in 148 cases was 1.31:1,and average age of onset was 2.52 ± 0.91 years old.Interval time between HFMD and onycholmadesis was 71.28 ± 62.69 days.Clinical manifestation of all 148 cases was separation of part or all of nail plates from roots in both hands and/or feet.Patients with shorter disease time only manifested transverse band of yellowing and discoloration or hollow area at nail roots.As time went on,some patients showed separation of near nail plate from root and even nail stripping.Conclusion Onychomadesis might be a late complication of HFMD.
展开▼
