对比探讨实时超声弹性成像与99Tcm-MIBI亲肿瘤显像在甲状腺占位性结节疾病中的诊断价值

摘要

目的 对比研究实时超声弹性成像技术与99锝m-甲氧基异丁基异腈(99Tcm-MIBI)亲肿瘤显像在甲状腺占位性疾病诊断方面的应用.方法 2009年8月至2010年7月对甲状腺占位性病变患者的186个结节进行实时组织弹性成像与99TcmMIBI亲肿瘤显像检查,判断甲状腺占位性病灶的良恶性,对2种技术做评价并探讨其临床价值,实时超声弹性成像技术采用0～4分评分法对弹性图像评分,99Tcm-MIBI亲肿瘤显像采用延迟比值法.所有结果均经手术后病理或细针抽吸细胞学证实.结果 良性病变共155个,恶性病变31个,实时超声弹性成像与99Tcm-MIBI亲肿瘤显像在特异性、准确性和阳性预测值的比较具有显著性差异,本组实时超声弹性成像优于99Tcm-MIBI亲肿瘤显像.结论 实时超声弹性成像技术应用组织硬度,99Tcm-MIBI亲肿瘤显像应用细胞功能显像,联合应用二者的优势对甲状腺结节占位性病灶的良恶性判断更为准确.%Objective To compare real-time elastography and 99 Tcm-MIBI in diagnosis of thyroid space-occupying nodules.Methods 186 thyroid nodules underwent both real time tissue elastography and 99Tcm-MIBI.We combined the two techniques to determine the benign or malignant nodules.All results were confirmed by postoperative pathology or fine needle aspiration cytology.Results 155 cases were benign lesions, 31 cases were malignant lesions.The difference of specificity ,accuracy and positive predictive value between real-time elastography and 99Tcm-MIBI was significant.The real-time elastographyis is better of 99Tcm-MIBI in diagnosis of thyroid space-occupying nod ules.Conclusions Real time tissue elastography imaging depends on the organization's hardness and 99 TcTm MIBI utilize functional imaging.The combin ation of their advantages could improve the accuracy in the diagnosis of thyroid spaceoccupying nodules.