AIM:To investigate the effects of early rehabilitative intervention on heart rate variability (HRV) and quality of life in patients with uncomplicated acute myocardial infarction(AMI). METHODS:One hundred and eighty-five consecutive patients with uncomplicated AMI were prospectively randomized into early rehabilitation group(Group 1,n=91) and controlled group(Group 2, n=94).Patients in the two groups were well-matched in terms of major basic materials.Patients in group 1 received early rehabilitation programme.Patients in group 2 received traditional rehabilitation programme.All subjects received 24-hour ambulatory electricardiogram (Holter) and HRV analysis within two weeks of onset of AMI,their self-care ability and psychosis were evaluated before discharge. RESULTS:No significant difference were found between the two groups in terms of all HRV data and Lown classification of ventricular arrhythmias >Ⅲ in Holter monitoring,but their self-care ability and psychosis were improved in early rehabilitation group. CONCLUSION:Early rehabilitation programme does not affect HRV in patients with uncomplicated acute myocardial infarction,thus does not affect myocardial electrical stability,meanwhile improve ability of self-care and quality of life.And it also suggests early rehabilitation programme is safe and feasible for patients with acute myocardial infarction from other view of point.%目的:探讨早期康复治疗对无并发症急性心肌梗死 (AMI )患者心率变异性( HRV)和生活质量的影响. 方法:185例研究对象前瞻性随机分为早期康复治疗组 (组 1, 91例 )及对照组 (组 2, 94例 ). 2组主要基线资料具可比性.组 1采用早期康复治疗方案,组 2采用传统康复方案.所有研究对象分别在入院 2周末行 24 h动态心电图( Holter)检查和 HRV分析.同时,患者出院前作生活自理能力和精神状态评价. 结果:早期康复组 HRV各指标、Holter中 Lown 3级以上室性心律失常发生率与对照组比较统计学上无显著性差异( P >0.05),但早期康复组能改善生活自理能力(χ 2=7.91,P < 0.05 )和精神状态(χ 2= 6.23,P < 0.05 ). 结论:无并发症 AMI 患者实行早期康复治疗不影响 HRV值,不影响心肌电稳定性,不增加 Lown 3级以上室性心律失常发生率,能改善患者生活自理能力和精神状态,从另一角度提示该组患者早期康复治疗安全可行.
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