运动训练肌肉拉伤动物模型构建的相关问题

摘要

背景:肌肉拉伤是常见的运动损伤之一,肌肉拉伤的动物模型是对其进行科学研究的重要途径.目的:分析与总结肌肉拉伤的机制和动物模型建立的相关问题.方法:计算机检索中国期刊全文数据库、Highwire以及PubMed 数据库1980-01/2010-12的相关文章,中文检索词为"肌肉拉伤、动物模型",英文检索词为"muscle strain,animal model".纳入与肌肉拉伤动物模型构建密切相关的研究.结果与结论:初检得到168篇文献,共保留31篇文献进行综述.目前国内外已有学者建立了一些骨骼肌损伤的动物模型,这些模型的建立对于骨骼肌的深入研究起到了极为重要的作用,但是肌肉急性拉伤动物模型的建立方法与运动实践相去甚远.因此,如何更有效地模拟高速运动状态下肌肉急性拉伤,建立一种符合运动实践特点的肌肉急性拉伤动物模型有其重要的实践价值.%BACKGROUND: Muscle strain is very common in sports. The animal model of the muscle strain is an important way for the scientific research. OBJECTIVE: To analyze and summarize questions related to mechanism and animal model establishment of muscle strain. METHODS:A computer-based online search of CNKI database, Highwire database and PubMed database was performed to collect articles published between January 1980 and December 2010 with the key words of “muscle strain, animal model” in Chinese and English, respectively. Articles that highly correlated with current status and the development of muscle strain animal model were considered. RESULTS AND CONCLUSION: A total of 168 articles were collected, and 31 articles were included to summary. Some scholars have created animal models of skeletal muscle injuries, which is useful for further research. However, acute animal model of muscle strain could not show the characters of sports in muscle strains. Therefore, it was very important to create an acute animal model that simulates exercise-induced acute strain, in order to provide basis for the further study on muscle structure, functions and pathology.