β-Kdo ethyl thioglycoside donor , in total yield of 24%and single selectivity of β-specific , was synthesized by a four-step reaction of condensation-decarboxylation , acetylation , methyl esterifica-tion and ethyl thioglycosylation , using oxaloacetic acid and D-arabinose as starting materials .The structure was confirmed by 1 H NMR and 13 C NMR.%以草酰乙酸和D-阿拉伯糖为原料,经缩合-脱羧,乙酰化,甲酯化和乙硫苷化等4步反应合成了β-Kdo乙硫苷供体,总收率24%,立体选择性单一,其结构经1 H NMR和13 C NMR确证。
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