对二氧环己酮与Nε-苄氧羰基-L-赖氨酸无规共聚物的合成及其共聚反应机理

摘要

通过对二氧环己酮与Nε-苄氧羰基-L-赖氨酸-N-羧酸酐本体共聚的方法制备了聚对二氧环己酮-Nε-苄氧羰基-L-赖氨酸的无规共聚物(PPCLAs),其结构1 H NMR和GPC表征.考察了聚合反应时间及催化剂用量对PPCLAs平均分子量的影响,并提出了"先竞争引发,再大分子间缩聚"的共聚反应机理.%The copolymers( PPCLAs) , poly( p-dioxanone-co-Nε-carbobenzoxy-L-lysine) , were synthe-sized by bulk copolymerization of p-dioxanone with Nε-carbobenzoxy-L-lysine-N-carboxyanhydride.The structures were characterized by 1 H NMR and GPC.The effects of catalyst quantities and reaction time on the average molecular weights of PPCLAs were investigated.The copolymerization mechanism was deduced as"competitive initiate-condensation polymerization between macromolecules".