Synthesis and Molecular Structure of (E)-1-(Morpholino)-2-(thiomethyl)-2-phenylvinylphosphonate

摘要

The title compound 2 (C15H22NO4PS, Mr = 343.38) was prepared by the reaction of α-benzoylthioformmorpholine 1 with trimethyl phosphite. The crystal is of monoclinic, space group P21/c with a = 14.906(2), b = 8.4711(12), c = 13.343(2) (A), β= 96.761(4)°, Z= 4, V=1673.1(5) (A)3, Dc = 1.363 g/cm3,μ(MoKα) = 3.06 cm-1, F(000) = 728, the final R = 0.0590 and wR = 0.1740 for 3036 observed reflections (I ＞ 2σ(I)). X-ray analysis revealed that the interatomic distance of C(5)-C(6) is 1.353(4) (A), indicating it is a normal C=C double bond. The P(1) atom takes a distorted tetrahedral geometry, and the morpholine ring adopts a chair conformation. The morpholino group is located at the 1-position of vinylphosphonate, and the phenyl and thiomethyl groups at the 2-position.