脊髓栓系综合征动物模型制作方法的研究进展

摘要

脊髓栓系综合征(TCS)是一种渐进性进展的神经发育障碍性疾病.目前TCS动物模型的制作方法主要有物理因素制作、化学因素制作和手术制作.这些动物模型普遍存在的问题是未能真实反映人类TCS渐进性进展的病程.未来该领域的研究方向是选取一个病因,单因素地分析该疾病,并逐步叠加,直至对该疾病有一个较深的了解.%Tethered cord syndrome (TCS) is a progressive neurodevelopmental disorder. The TCS model was established mainly using physical and chemical methods and surgery, but remained problems in failing to fully reflect the progressive course of the human TCS. In the future, it may select a single etiological factor to analyze, and gradually add other factors until we have deeper understanding of this dis-ease.