显微镜下微创肿瘤切除术对矢状窦旁及大脑镰旁脑膜瘤患者症状改善、Simpson分级和预后的影响

摘要

目的 分析显微镜下微创肿瘤切除术对矢状窦旁及大脑镰旁脑膜瘤患者症状改善、Simpson分级和预后的影响.方法 选取山西省人民医院2012年12月至2016年12月收治的矢状窦旁及大脑镰旁脑膜瘤患者123例为研究对象,采用随机数字表法分为对照组(行传统开颅手术)61例和研究组(行显微镜下微创肿瘤切除术)62例,比较两组症状改善、Simpson分级及术后复发情况.结果 两组手术时间差异无统计学意义(t=1.13,P ＞0.05),研究组术中出血量[(119.05±26.94) mL]较对照组[(172.05±27.43) mL]少(t=10.81,P＜0.01);研究组术后四肢运动(3.22％)、癫痫(4.65％)、感觉障碍(1.61％)等症状改善情况明显优于对照组(14.75％、31.15％、27.87％)(x2=5.02、6.34、4.14,均P＜0.05);研究组肿瘤Simpson分级切除率优于对照组(x2=12.23,P＜0.01);术后研究组癫痫发作(0.00％)、颅内出血(1.61％)等并发症发生率、复发率(0.00％)均较对照组(26.23％、27.87％、27.87％)低(x2=4.05、4.14、4.65,均P＜0.05).结论 显微镜下微创肿瘤切除术能够有效改善矢状窦旁及大脑镰旁脑膜瘤患者临床症状,提高肿瘤切除率,有效减轻术后并发症发生率及复发率.%Objective To analyze the effects of minimally invasive tumor resection under microscope on symptoms improvement,Simpson classification and prognosis in patients with sagittal sinus and falx cerebri meningioma.Methods From December 2012 to December 2016,123 patients with parasagittal and falx meningioma in the People 's Hospital of Shanxi Province were randomly divided into two groups according to the digital table.The control group (61 cases) underwent conventional craniotomy,and the study group (62 cases) performed minimally invasive tumor resection.The symptoms improvement,Simpson classification and postoperative recurrence were compared between the two groups.Results The operation time between the two groups had no statistically significant difference (t =1.13,P ＞ 0.05).The intraoperative blood loss in the study group was (119.05 ± 26.94) mL,which was lower than (172.05 ±27.43) mL in the control group (t =10.81,P ＜ 0.01).The postoperative symptoms improvement of movement of limbs (3.22％),epilepsy (4.65 ％),sensory dysfunction (1.61％) in the study group were significantly better than those in the control group (14.75％,31.15％,27.87％) (x2 =5.02,6.34,4.14,all P ＜ 0.05).The Simpson classification of tumor resection rate in the study group was better than that in the control group(x2 =12.23,P ＜0.01).The incidence rates of complications such as epilepsy(0.00％) and intracranial hemorrhage(1.61％),and recurrence rate(0.00％) in the study group were lower than those in the control group(26.23％,27.87％,27.87％)(x2 =4.05,4.14,4.65,all P ＜ 0.05).Conclusion Minimally invasive tumor resection under the microscope can effectively improve clinical symptoms of patients with sagittal sinus and falx cerebri meningioma,which can improve tumor resection rate,effectively reduce the incidence of postoperative complications and recurrence rate.