焦虑抑郁影响初诊高血压患者降压效果分析

摘要

目的：探讨焦虑抑郁对初诊原发性高血压患者降压效果的影响。方法初次诊断原发性高血压患者122例，A组为单纯高血压者65例，B组为高血压并焦虑抑郁者57例，观察左旋氨氯地平治疗8周对诊室血压控制率的影响。结果治疗前A组平均收缩压为（163.9±10.5）mmHg ，平均舒张压为（98.4±6.2）mmHg ，治疗8周后分别为（139.6±8.1）mmHg和（84.3±5.7）mmHg（P均＜0.01），血压控制达标率为78.26％；B组平均收缩压为（166.3±10.9）mmHg ，平均舒张压为（99.6±6.9）mmHg ，治疗8周后分别为（149.6±9.1）mmHg和（89.3±6.7）mmHg（P均＜0.05），血压控制达标率为42.39％。结论焦虑抑郁可显著影响初诊原发性高血压患者的血压控制效果。%Objective To investigate the influence of anxiety and depression on the control of blood pressure in patients with primary hypertension.Methods Patients with Initially diagnosed primary hypertension were divided into group A (pure hypertension ,n=71) and group B (Hypertension combined with anxiety and depression ,n=51). Blood pressure and the con-trol rate were measured after treatment with Levoamlodipine for 8 weeks.Results Before treatment ,the mean systolic and di-astolic blood pressure of group A were(163.9 ± 10.5)mmHg and(98.4 ± 6.2)mmHg ;after treatment ,the mean systolic and diastolic blood pressure was respectively (139.6 ± 8.1)mmHg and(84.3 ± 5.7)mmHg after treatment for 8 weeks(P<0.01). while before treatment ,the pressures of group B were(166.3 ± 10.9)mmHg and (99.6 ± 6.9)mmHg respectively ;after treat-ment ,they were (149.6 ± 9.1)mmHg and (89.3 ± 6.7)mmHg ,respectively. The control rate was 84% and 62% in group A and B.Conclusion Comorbidity of anxiety and depression has adverse impact on the control of blood pressure in patients with initially diagnosed primary hypertension.