Objective To compare the haemodynamics indexes and anesthetic effects of patients with knee arthroscopy un‐der combined spinal-epidural anesthesia and lumbar plexus combined sciatic nerve block under ultrasonic puncture. Methods 80 patients with knee arthroscopy were collected and randomly divided into two groups according to the different anesthetic methods, the lumbar plexus combined sciatic nerve block group (Group A) and the combined spinal-epidural anesthesia group (Group B), with 40 patients in each group. The haemodynamics indexes, onset time, maintenance time, anesthetic effect, ad‐juvant drugs, infused amount and adverse reaction in both groups were recorded and compared. Results Group A was better in the haemodynamics indexes and with less adverse reactions. Conclusion Lumbar plexus combined sciatic nerve block method under ultrasonic puncture has perfect block and anesthetic effects in knee arthroscopy surgery, with steady haemodynamics in‐dexes and less adverse reactions. The method is suitable for patients with a long operation time.%目的：比较超声引导下腰丛联合坐骨神经阻滞对比腰‐硬联合麻醉对膝关节镜手术患者血流动力学及麻醉效果。方法80例接受膝关节镜手术患者，根据其麻醉方式不同分为腰丛联合坐骨神经阻滞麻醉（A组）及腰‐硬联合麻醉（B组），2组均40例。记录并比较2组患者麻醉后血流动力学指标、药物起效维持时间、麻醉效果、辅助用药情况、补液量以及不良反应。结果2组患者血流动力学比较，A组优于B组，A组并发症少于B组。结论超声引导下腰丛联合坐骨神经阻滞用于膝关节镜手术麻醉，阻滞完善，麻醉效果确切，血流动力学平稳，并发症少，适合手术时间相对长的患者。
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