如何提高卵巢癌肉瘤治疗疗效

摘要

卵巢癌肉瘤是临床极为罕见但恶性程度极高的一类肿瘤,因组织成分同时含有癌和肉瘤两种成分,使其在治疗及预后方面不同于其他的妇科恶性肿瘤.临床上卵巢癌肉瘤的恶性程度更高,对放化疗的敏感性更低以及预后更差.目前对卵巢癌肉瘤的治疗方法主要以手术治疗为主,同时术后行辅助治疗.得益于卵巢癌肉瘤相关基因的异常表达,靶向治疗在改善卵巢癌肉瘤预后方面表现出新兴优势.%Ovarian carcinosarcoma (OCS)is highly aggressive and rare tumors differing from other malignant gynecological tumors,which are composed of both epithelial and mesenchymal elements.Clinically OCS is more aggressive and less sensitivive to chemotherapy and radiotherapy with worse prognosis.The treatment for carcinosarcoma is mainly composed of surgery and adjuvant therapy.With the advanced research on the gene expression,targeted therapies present a promising potential for the improvement of the prognosis.