目的 探讨尿素注射联合手术治疗眼部动静脉血管畸形伴动静脉瘘的方法,评价手术治疗的临床效果.方法 回顾性分析201 1年1月至2016年12月诊治的42例眼部动静脉血管畸形伴动静脉瘘的病例资料,针对每例患者病变范围及严重程度制定个体化治疗方案.3例弥漫性严重病变患者,放弃手术治疗.另39例先行局部静脉区病变内注射40％尿素溶液治疗,注射量为3 ～6 ml,每天1次,每次0.5 min,连续注射治疗7～10d后,行手术切除病变.结果 共39例患者尿素注射后行手术治疗,其中21例一期手术完全切除,18例于3个月后择期二期手术切除.术后随访3个月至1.5年,症状无复发.结论 尿素注射联合手术治疗的方法,可以有效地治疗眼部动静脉血管畸形伴动静脉瘘.%Objective To explore the treatment of the ocular arteriovenous malformation using urea injection combined with surgical procedures and evaluate clinical effects.Methods 42 cases withocular arteriovenous malformation combined with fistula were retrospectively analyzed between January 2011 and December 2016.Individual treatments were formulated according to leision areas and severity.3 cases with diffuse malformations were excluded from the study,because no surgical procedures were performed.39 cases underwent local injection with 40％ urea before resection.The urea was injected locally into vein malformation area by means ofmulti-point injection on a basis of 30 seconds,3-6 ml for each treatment,once a day.The injection was performed for successive 7-10 days.The therapeutic effects and cosmetic result were recorded.Results 23 cases occurred intheright ocular area and 16 cases in left.21 cases were removed radically in single operation.No recurrenceoccurredin any case with follow-ups of 3 months to 1.5 years.Cosmetic result with ocularbilateral symmetrywere satisfactory.Conclusions Combined treatment with urea injection and surgical procedure could effectively treat ocular arteriovenous malformation with arteriovenousfistula.
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