Institute of Pharmacology&Toxicology;
Col-lege of Pharmaceutical Sciences;
Key Laboratory of Medical Neurobiology of the Ministry of Health of China;
Zhejiang University;
Hangzhou 310058;
China;
Department of Pharmacy;
the First Affili-ated Hospital;
School of Medicine;
Zhejiang Univer-sity;
Hangzhou 310003;
China;
bortezomib; peripheral neuropathy; sciatic nerves; demyelination; Schwann cells; lysosome;