This paper reports 9 female cases of giant fibroadenoma of breast.The patients were 13(2 cases),14(5)and 15(2)years old respectively.The longest course of the condition was 6 years and the shortest 1 month in this series.All appeared as a rapid growing mass occupying more than half of the affected breast within a short time.Six tumors were found in the right breast and 3 in the left.Clinical manifestation was characterized by giant mass in the breast with nodular or qobulous appearance.Skin congastion and phlebectasis on the tumor were seen in 3 cases,1 case complicated with ulceration.The resected specimen measurement was from 8 cm to 14 cm in diameter(average 10.6 cm),and microscopic findings showed that 7 cases belonged to intraductal type,and 2 to periductal.The latter was rich in fidrous cells anb showed mitoses.One of the 2 periductal type patients showed epithelial proliferation of glandular duct and feature of mitosis.rnSimple mastectomy was performed on 2 patients and tumor excision on 7.All the patients were followed up for an average length of 5 years and 7 months.There was no recurrence.The affected breast subject to tumor excision basically developed as well as the contralateral breast and had a,good appearance.rnThe authors noted that the tumor's development be attributed to disturbance of endocrine regulation,especially the stimulation of estrogen.They emphasized the diagnosis be based upon the combination of clinical features,the diameter of the tumor and pathological findings.Excision of the tumor is choice treatment with good result.%@@ 河北医学院笫二医院病理科魏守礼我院自1974～1982年底,收治9例小儿乳腺巨大纤维腺瘤(以下简称GFA).现报道如下.rn临床资料rn9例女孩.年龄:13岁2例、14岁5例、15岁2例.病程最长的1例为6年,其余均在1年以下,最短者1月.发生在右侧乳房者6例,左侧3例.有3例合并对侧乳房纤维腺瘤.肿瘤占据全乳房者6例,3/4者1例,1/2者2例.
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