Histologic studies of normal colon and rectum in 34 infantile cadavers by optical microscope showed that there were more morphologically typical and atypical ganglion ceils in both Auerbach and Meissner's plexuses.The staining of Nissl's bodies can help identify atypical ganglion cells.As the child grows older,these cells become larger.Typical ones increase proportionally.The nearer to the cephalic part of the lurge intestine,the greater its proportion,which demonstrates the ganglion cells are in the course of maturity.The number of Auerbach and Meissner's plexuses vary in different age groups and at different sites,and so does the number of ganglion cells.Therefore,the age of the patient and site examined should be considered in the assessment of the number of ganglion cells.Absence of these cells in the abovementioned plexuses was noticed in the spasmodic segment of the intestines on the histopathological examination of 23 cases of Hirschsprung's disease.Simultaneously,the nerve fibers there remarkably increased in number and size,interwoven into wave-like bundles.But 25 cm above the spasmodic segment,the intestine had a normal lumen,and the number and morphology of the plexuses and ganglion cell_s are within normal limits.%@@ 先天性巨结肠主要病理改变是神经节细胞缺如,但有关小儿正常直肠结肠的神经丛神经节细胞的组织学研究,国内外报道不多,本文对正常小儿与先天性巨结肠症直肠、结肠神经丛进行组织学观察.
展开▼
