儿童肌挛缩症病因探讨(附动物实验报告)

摘要

Differnet kinds of stimulants,such as injecting penicillin and repeated stimulati on with needle on the muscle of three extremities were used in 20 young rabbits during a period of 20 days.The results showed that the pathological changes and physical signs of muscular contracture in rabbits were almost the same as those changes in children.Therefore animal model of muscular coatracture was obtained successfully.rnAmong those stimulants,penicillin diluted by 2% Benzyl alcohol may be the most dangerous causative factor of this disease.It is possible to reduce the incidence of muscular contracture in future,if we do not use peniciltin diluted by 2% Benzyl alcohol.%作者采用不同刺激因子,反复作用于动物不同肢体的肌肉部分,得到了与儿童注射性臀肌挛缩症临床表现、病理改变相一致的结果,成功地建立了此症的动物模型,提供了注射因素作为肌挛缩症病因的实验依据.同时发现以2%苯甲醇作青霉素溶媒是最危险的致病因子,提示今后不再使用此溶媒,可望降低本病发生率.