先天性巨结肠症状与病变肠段关系分析

摘要

先天性巨结肠(HD)症状的严重程度与病变肠段之间关系知道甚少.对202例HD患儿的症状与14项临床和病理因素进行逐步回归和Logistic分析,发现HD的症状严重程度与狭窄段移行段总长、肠道炎症等8项因素有关,而与狭窄段长度、狭窄段中神经纤维增生程度等6项因素无关.这在理论上解释了某些手术成败的原因,对临床治疗HD有一定的指导意义.%Fourteen selected items of the clinical and pathological criteria of 202 Hirschsprung's disease(HD)with different severity of symptoms were analysed by stepwise regression and logistic regression.The severity of HD symptoms was significantly correlated with 8 items in cluding the length of the narrow and transitional segment,enterocolitis,and etc.but not with the other 6 factors including the narrow segment and density of nerve fibers in the narrow segment.This result may explain theoritically the success or failure of some operations for HD and may guide the treatment of HD.