目的 探讨采用异种脱细胞真皮基质修复耳廓/外耳道肿物切除术后皮肤缺损的临床效果.方法 收集2013年1月至2016年3月应用异种脱细胞真皮基质修复耳廓/外耳道良、恶性肿物切除术后皮肤缺损的32例患者资料,其中耳廓肿物14例,外耳道肿物18例,术后随访观察6个月,评价异种脱细胞真皮基质植入后效果.结果 术后观察至6个月,所有患者创面愈合良好,无明显疤痕和挛缩,无外耳道狭窄及闭锁,无移植区排斥反应,亦无全身不良反应.结论 异种脱细胞真皮基质是修复耳廓/外耳道肿物手术切除后皮肤缺损简单、安全、可靠的方法,并可获得较为满意的效果.%Objective To report application of heterogeneous acellular dermal matrix grafts in skin defect repair af-ter resection of external ear neoplasms. Methods From January 2013 to March 2016, 32 patients (14 with auricular neo-plasms and 18 with external auditory canal neoplasms) received heterogeneous acellular dermal matrix grafts for skin de-fect repair after removal of external ear neoplasms, and were followed-up for 6 months. Results The wound healed well in all patients, with no obvious scar or contracture, external auditory canal atresia or stenosis, nor reject reaction of trans-plantation. None of the 32 patients showed significant systemic adverse reaction. Conclusions Heterogeneous dermal acellular matrix transplant can be used as a simple, safe and reliable method for repairing skin defect after removal of ex-ternal ear neoplasms, and is worth broad clinical applications.
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