北京市海淀区1639例汉族中老年男性骨密度调查分析

摘要

Objective To research the bone mineral density (BMD) of 1639 middle-aged men with Han nationality in Haidian district, Beijing, and to explore the incidence and influential factors of osteoporosis (OP) in this district. Methods A total of 1639 middle-aged men with Han nationality, who received health examination in our hospital from March to June 2012, were enrolled. BMD of the distal one-third of the radius and the ulna in non -dominant forearm was measured with DXA ( ExA-3000, Osteosys Co. Korea). An information collection table was established , and BMD, height, weight, body mass index ( BMI) , the status of smoking, tea drinking, milk drinking, and exercise were recorded. All the subjects were divided into several groups according to a 10-year-age division. BMD, T-score, incidence and related influential factors of each group were analyzed . Results The incidence of OP in 40 -49-year-old group, 50 -59-year-old group, 60 -69-year-old group, 70 -79-year-old group, and over-80-year-old group was 12. 19% , 21. 54% , 40. 72% , 55. 56% , and 69.73%, respectively. The height, weight, BMI, regular exercise were positively correlated with BMD ( r = 0. 18, 0. 19, 0. 12, 0. 24, respectively, P < 0. 05 ). Smoking was negatively correlated with BMD ( r = - 0. 19, P < 0. 05 ). Drinking of tea and milk had no obvious correlation with BMD ( P > 0. 05 ). Conclusion BMD in each group declines with the increase of age. The incidence of OP is significantly increased ( x = 343. 88, P < 0. 05 ). Lifestyle is obviouslycorrelated with BMD. Measurement of BMD should be one item of routine examination for middle -aged people. Early discovery, active intervention and advocacy of healthy lifestyle have an important meaning for the prevention and treatment of OP.%目的 调查北京市海淀区1639例汉族中老年男性骨密度,探讨本地区骨质疏松发病率及影响因素.方法 选择2012年3月～6月在我院体检的1639例汉族中老年男性为研究对象,采用韩国osteosys公司生产的ExA-3000型骨密度仪,检测受试者非受力侧前臂尺桡骨中远端三分之一处骨密度,建立信息采集表,记录体检人群骨密度、身高、体重、体重指数(BMI)、吸烟、饮茶、喝牛奶、运动情况,将检测结果以每10岁为1年龄段分组,分析每组骨密度、t评分、患病率及相关影响因素.结果 男性40～49岁年龄段骨质疏松发病率为12.19%;50～59岁年龄段男性骨质疏松发病率为21.54%;60～69岁年龄段骨质疏松发病率为40.72%;70～79岁年龄段骨质疏松发病率为55.56%;80岁以上年龄段骨质疏松发病率为69.73%.身高、体重、BMI和规律性运动与骨密度呈正相关(r=0.18,r=0.19,r=0.12,r=0.24,P＜0.05);吸烟与骨密度呈负相关(r=-0.19,P＜0.05);饮茶、喝牛奶与骨密度无明显相关性(P＞0.05).结论 随着年龄的增加,每个年龄段中老年男性骨密度均呈下降趋势,骨质疏松发病率明显上升,差异具有统计学意义(χ2=343.88,P＜0.05).生活方式和骨密度有明显的相关性.因此,将骨密度检测作为中老年人体检的常规检查项目,早期发现,积极干预,倡导健康生活方式,对于防治骨质疏松具有重要意义.