住院老年人生活方式与骨质疏松的偏相关分析

摘要

目的 了解桂林老年人生活方式与骨质疏松的关系. 方法 选取我院246例住院老年患者(≥60岁) ,在24小时内调查其性别、年龄、身高、体重、既往1年服用可能对骨质有影响的他汀类降脂药、质子泵抑制剂、肝素、避孕药、激素、含维生素D3 的钙片等及吸烟、饮酒、喝浓茶、碳酸饮料、牛奶、吃水果、蔬菜、运动、睡眠、摔跤、骨折等情况,同时测量L2-L4、双侧股骨颈、粗隆及Ward' s三角区的骨密度( T-score) ,取两者T-score低值,按60~79岁组、≥80岁组及全部老年人组,与前述调查指标进行偏相关分析,并比较骨质疏松、骨量减少、骨量正常3组上述指标有无差异. 结果 3组患者均与性别、体重、喝浓茶等因素相关(P<0.05),≥80岁组及全部老年人组骨密度与服用他汀类降脂药、含维生素D3 的钙片、饮酒、运动等因素相关(P<0.05),全部老年人组还与喝牛奶因素相关(P<0.05);按骨质疏松、骨量减少、骨量正常组间比较,性别、身高、体重、服用他汀类降脂药、饮酒、喝浓茶、牛奶、运动8项因素有统计学意义(P<0.05),把上述8项因素在组间进行两两比较,性别因素在各组均有统计学差异,身高、饮酒、运动3项因素在骨质疏松组和骨质正常组有统计学意义( P<0.01 ) ,体重在骨质疏松组与骨量减少组、骨质疏松组与骨量正常组有统计学意义,服用他汀类药物、喝浓茶、牛奶3项因素在骨质疏松组与骨量正常组、骨量减少组与骨量正常组有统计学意义( P<0.05 ). 结论 本组老年人骨质疏松或骨量减少与性别、体重、服含维生素D3 的钙片、喝浓茶等因素相关,饮酒、喝浓茶、牛奶、服用他汀类降脂药、运动对骨质疏松可能有预防作用.%Objective To study the relationship between lifestyle and osteoporosis in elderly people in Guilin.Methods Two hundred and forty-six elderly patients (≥60 years old) in the hospital were selected.Sex, age, height, weight, drug intake during last 1 year ( including statins, proton pump inhibitors, heparin, contraceptives, hormones, calcium, and vitamin D3 ) , smoking, alcohol drinking, dense tea, carbonated drinks, milk, fruit, vegetables, exercise, sleep, wrestling, and fracture were investigated in 24 hours.Bone mineral density ( T-score) of L2-L4, bilateral femoral neck, trochanter, and Ward's triangle region was detected. The lowest value was required.All patients were divided into three groups (all patients, 60-79 years old, and ≥80 years old). Partial correlation analysis was performed between the factors mentioned and osteoporosis, osteopenia, and the normal bone mass in the 3 groups.Results Sex, weight, and tea drink were significantly correlation with three groups ( P <0.05 ) .BMD was significantly correlated with intake of statins, calcium and vitamin D3, wine, and exercise in ≥80 years old group and all patient group (P<0.05).Milk drinking was significantly correlated with BMD in all patient group.Sex, height, weight, taking drugs of statins, wine, tea, milk, exercise were significantly different among osteoporosis, osteopenia, and the normal mass group ( P<0.05).Sex was significantly different between any two of the three groups.height, wine, and exercise were significantly different between osteoporosis and the normal bone mass group ( P<0.01 ) .Weight was significantly different between osteoporosis group and osteopenia group, osteopenia group and the normal bone mass group.Intakes of statins, tea, and milk were significantly different between osteoporosis group and the normal group, osteopenia group and the normal group ( P<0.05 ) .Conclusion Osteoporosis or osteopenia in the elderly was related to sex, weight, calcium and vitamin D3 , tea drinking.Intakes of wine, tea, milk, and statins and exercise may prevent from osteoporosis.