首页> 中文期刊> 《中华眼视光学与视觉科学杂志》 >前房深度对有晶状体眼后房型人工晶状体植入术后前房形态的影响

前房深度对有晶状体眼后房型人工晶状体植入术后前房形态的影响

摘要

Objective To observe the impact of preoperative anterior chamber depth (ACD) on anterior chamber angle morphology after phakic posterior chamber implantable collamer lens (PPC-ICL) implantation. Methods One hundred and thirty-two eyes of 80 consecutive patients with myopia undergoing PPC-ICL implantation were enrolled in this retrospective study. The patients were divided into three groups according to preoperative anterior chamber depth: group A: ACD<3.0 mm; group B:3.0≤ACD<3.5 mm; group C: ACD≥3.5 mm. Before surgery and 3 months after surgery, anterior segment optical coherence tomography (AS-OCT) was used to measure anterior segment morphology. The indexes observed included ACD, angle opening distance (AOD500), trabecular-iris space area (TISA500) and scleral spur angle (SSA) in the 0° and 180° positions. Analysis of variance, correlation analysis and a paired t-test were used for statistical analysis. Results For all the patients, the measured values of preoperative AOD500 (0°, 180°) (r=0.51, 0.47), TISA500 (0°, 180°) (r=0.55, 0.52) and SSA (0°, 180°) (r=0.46, 0.58) were positively correlated with ACD (P<0.01). Three months after surgery, the average ACD, AOD500, TISA500 and SSA values of the three groups had significantly decreased compared to preoperative values (P<0.05). The measurements of AOD500 (F=7.00, 5.08), TISA500 (F=6.42, 3.06) and SSA (F=7.20, 4.73) in the 0° and 180° positions in group A were significantly lower than those in groups B and C (P<0.05), and there was no significant difference between group B and group C. The postoperative AOD500, TISA500 and SSA in the three groups declined in the same proportion, and there were no statistically significant differences. The PPC-ICL vaults in groups A and B were lower than those in group C (F=5.37, P<0.05). Three months after surgery, the changes (percentage) in AOD500 (r=0.54, 0.50), TISA500 (r=0.49, 0.48) and SSA (r=0.60, 0.61) were positively correlated with ICL vault (P<0.01). No anterior chamber angle closure was found during the follow-up period, and there was no significant decrease in intraocular pressure in the three groups after surgery. Conclusion The morphology of the anterior chamber changes significantly after PPC-ICL implantation. Patients with a shallow anterior chamber will show a shallower anterior chamber depth and narrower anterior chamber angle after surgery. The change in anterior chamber morphology will be more obvious in patients with a higher vault.%目的:观察术前前房深度(ACD)对有晶状体眼后房型人工晶状体(PPC-ICL)植入术后房角形态的影响。方法回顾性系列病例研究。连续选取已接受PPC-ICL植入术的近视患者80例(132眼)。根据患者术前ACD分为3组:A组:ACD<3.0 mm;B组:3.0≤ACD<3.5 mm;C组:ACD≥3.5 mm。术前和术后3个月时分别采用前节光学相干断层扫描仪(AS-OCT)对患者进行眼前节生物测量。检测指标包括中央 ACD、0°与180°方位房角开放距离(AOD500)、虹膜小梁空间面积(TISA500)和巩膜突角(SSA)。使用方差分析、直线相关分析和配对t检验对数据进行分析。结果所有患者术前AOD500(0°、180°)(r=0.51、0.47),TISA500(0°、180°)(r=0.55、0.52)和SSA(0°、180°)(r=0.46、0.58)测量值均与ACD呈正相关(P<0.01)。术后3个月时,3组患者平均ACD、AOD500、TISA500以及SSA测量值较术前均下降(P<0.05)。3组患者的AOD500(F=7.00、5.08)、TISA500(F=6.42、3.06)以及SSA(F=7.20、4.73)差异有统计学意义(P<0.05),其中A组患者的3个指标值均低于B组和C组(P<0.01),而B组和C组相比差异无统计学意义。3组患者的AOD500、TISA500和SSA在术后发生相同比例的下降,差异无统计学意义。3组拱高差异有统计学意义(F=5.37,P<0.05),A组和B组拱高均显著低于C组(P<0.05)。术后3个月时AOD500(0°、180°)(r=0.54、0.50),TISA500(0°、180°)(r=0.49、0.48)及 SSA (0°、180°)(r=0.60、0.61)手术前后变化率均与拱高呈正相关(P<0.01)。3组患者随访期内均未见房角关闭,手术前后眼压差异均无统计学意义。结论 PPC-ICL植入术后房角形态发生显著改变,浅前房患者术后前房更浅、房角更窄,且拱高较高者术后前房形态改变更为明显。

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