视觉电生理检查在青光眼早期诊断中作用的研究进展

摘要

Glaucoma can lead to irreversible visual impairment.The pathogenesis of glaucoma is complicated and it is difficult to diagnose early.As an objective and functional examination tool,visual electrophysiology has its own advantages to detect early glaucomatous damage.It can indicate early functional degeneration of retinal ganglion cells and can direct doctors to diagnose and give treatment to glaucoma patients.It has been proved that the pattern electroretinogram,photopic negative response and multifocal electroretinogram can provide most of the information in the early diagnosis of glaucoma.This article overviews the latest application progress of these three visual electrophysiological techniques.%青光眼是不可逆性致盲眼病,发病机制复杂,早期诊断困难.视觉电生理检查作为客观视功能检查手段,可通过检测青光眼早期视网膜神经节细胞功能损伤,对青光眼的临床早期诊断、早期干预发挥指导作用,在评价青光眼早期损伤方面具有优势,其中图形视网膜电图、明适应负波反应和多焦视网膜电图可提供重要信息.本文结合最新相关文献报道,对视觉电生理检查在检测早期青光眼损伤中的作用及研究进展进行综述,以期为临床工作及开展相关研究提供参考.