联合应用OERPs和T T嗅觉计在嗅觉减退评估诊断中的价值探讨

摘要

Objective To explore the clinical value of combined application of olfactory event-related potentials ( OERPs ) and T&T olfactometory for evaluating olfactory function. Methods The study included 146 patients presenting with olfactory disorder by medical history, physical examination, olfactory testing and medical imaging. Olfactory testing was performed using T&T Olfactometory and OERPs. Results Accordance between olfactory psychophysical measurements and OERPs was observed in 142 patients. However, a special phenomenon was observed in 4 patients. The subjective results were basically normal including detection thresholds and differential thresholds, however, the olfactory event-related potentials were absent. Conclusions The measurement of OERPs might play a significant role in evaluating olfactory dysfunction. Combined application of OERPs and T&T olfactometory may diagnose olfactory dysfunction more exactly.%目的 探讨联合应用嗅觉事件相关电位(OERPs)和T & T嗅觉计在嗅觉减退评估诊断中的价值.方法通过病史采集、耳鼻喉科常规检查、鼻窦CT、嗅球及嗅束MRI检查,分析嗅觉减退患者的病程、病因,联合应用T&T嗅觉计和OERPs测试法对嗅觉减退患者的嗅觉功能进行量化评估和分析.结果在本组146例患者中,142例患者的主观识别阈及察觉阈结果和客观OERPs检查结果基本一致;但在4例患者中,观察到主观识别阈及察觉阈检查结果基本正常,而OERPs反应波形却不能引出的特殊现象.结论 OERPs作为一项客观检查,在进行嗅觉功能的评估方面具有不可忽视的重要作用.联合应用OERPs和T&T嗅觉计评估嗅觉功能对嗅觉减退的诊断更精确.