维脑路通联合地塞米松球周注射治疗白内障术后角膜水肿

摘要

目的 评价维脑路通联合地塞米松球周注射治疗白内障术后角膜水肿的临床效果.方法 将白内障晶状体超声乳化术后严重角膜水肿198例(200眼)随机分对照组和观察组,后者在前者基础上加用球周注射维脑路通联合地塞米松.观察两组各100眼角膜水肿消退的时间及术后1、3、5、7d角膜恢复透明的眼数,并进行对比.结果 观察组比对照组角膜水肿消退的时间短,术后1d:角膜水肿患眼100眼对100眼,无差异;术后3 d:45眼对15眼,t=21.43;术后5 d:66眼对32眼,t=23.13;术后7d:82眼对45眼,t=29.53;均为P＜0.005.从术后3d起角膜恢复透明的眼数差异有统计学意义.结论 维脑路通和地塞米松对白内障术后角膜水肿恢复有较好的疗效.%Objective To investigate the clinical efficacy of Troxerutin combined with Dexamethasone for corneal edema after phacoemulsification.Methods Two hundred eyes of 198 cases of serious corneal edema after cataract phacoemulsification were randomly divided into the control group and the observation group.The patients in the observation group received peribulbar injection of Troxerutin and Dexamethasone additionally except the treatments in the control group.The fading time of corneal edema of 100 eyes in each group and the number of eyes with transparent cornea at 1,3,5 and 7 d after the surgery were observed and compared.Results The fading time of corneal edema in the observation group was shorter than that in the control group.On one day after the surgery,the number of eyes with transparent cornea was 100 in each group.The numbers of patients with corneal edema were 45 versus 15 (t =21.43),66 versus 32 (t =23.13) and 82 versus 45 (t =29.53),respectively,on the 3,5,7th d after surgery in the control group and observation group and the differences were statistically significant (P ＜ 0.005).Conclusion Troxerutin and Dexamethasone for the recovery of corneal edema after cataract surgery is effective.