~(18)F-FDG PET/CT及增强CT诊断原发性肝癌及肝癌术后复发的价值

摘要

Objective To compare diagnostic value of ~(18)F-fluoredeoxyglucose (FDG) PET/CT with contrast-enhanced CT in detecting primary hepatic carcinoma and postoperative recurrence.Methods Twenty-five cases of primary hepatic carcinoma or postoperative recurrent tumor underwent whole-body ~(18)F-FDG PET/CT and contrast-enhanced CT within one week's interval.They were retrospectively reviewed and the difierences between these two modalities were investigated.Results Of these 25 cases,there were 13 cases with primary hepatocellular carcinoma.1 case with intrahepatic cholangiocarcinoma and 11 cases with postoperative recurrence.The sensitivity of 18 F-FDG PET/CT and contrast-enhanced CT in diagnosing primary hepatic carcinoma was 78.6%(11/14) and 92.9%(13/14),and sensitivity in diagnosing postoperative recurrent was 100.0%(11/11) and 63.6%(7/11) respectively.Conclusion Contrast-enhanced CT may have a slight advantage over PET/CT in detecting primary hepatic carcinoma,but ~(18)F-FDG PET/CT combined with contrast-enhanced CT has even greater accuracy.Meanwhile,~(18)F-FDG PET/CT has better diagnostic accuracy in detection of postoperative recurrent tumor.%目的 比较~(18)F-脱氧葡萄糖(FDG)PET/CT与增强CT对原发性肝癌或肝癌术后复发的诊断价值.方法 回顾性分析诊断为原发性肝癌或肝癌术后复发且进行~(18)F-FDG PET/CT与增强CT检查的病例共25例,2种检查间隔时间在1周内.其中原发性肝癌经手术或穿刺证实,肝癌术后复发经临床随访证实.结果 25例患者中,确诊为原发性肝癌14例,其中肝细胞肝癌13例,胆管细胞癌1例;肝癌术后复发11例.~(18)F-FDG PET/CT对原发性肝癌的诊断阳性率为78.6%(11/14),增强CT阳性率为92.9%(13/14).在肝癌术后复发中,~(18)F-FDG PET/CT诊断阳性率为100.0%(11/11),增强CT阳性率为63.6%(7/11).结论 在原发性肝癌诊断中,增强CT优于~(18)F-FDG PET/CT,~(18)F-FDG PET/CT显像联合增强CT可明显提高诊断率.而住肝癌术后复发检测中,~(18)F-FDGPET/CT优于增强CT.