目的：探讨无创正压通气治疗急性左心衰竭的效果。方法选取急性左心衰竭患者64例，随机分为观察组（32例）和对照组（32例）。对照组给予吸氧、强心、利尿、扩血等常规治疗，观察组在常规治疗的同时应用无创正压通气治疗，观察两组治疗前、治疗后24 h及72 h心率、呼吸、血压、血氧饱和度变化情况及心功能改善情况。结果观察组治疗后24 h后的总有效率为93．75％，高于对照组的71．87％，差异有统计学意义（ P＜0．05），观察组治疗72 h后PaO2、PaCO2、pH、BNP 明显优于对照组，差异有统计学意义（ P＜0．01）。结论无创正压通气配合常规治疗能明显改善急性左心衰竭患者的症状，挽救患者的生命。%Objective To investigate the efficacy of treatment of acute left ventricular failure by non-invasive positive pressure ventilation ( NIPPV) .Methods Sixty-four patients with acute left ventricular failure were randomly divided into the observation group(n=32) and the control group(n=32).The control group was treated by conven-tional therapy,including oxygen inhalation ,strengthening myocardial contraction ,diuresis,vasodilator and so on; the observation group was treated by NIPPV on the basis of conventional therapy .The changes in heart rate , respiration, blood pressure , blood oxygen saturation and the heart function were observed before treatment , at 24 hours and 72 hours after treatment,respectively.Results At 24 hours after treatment, the total effective rate in the observation group was higher than that in the control group (93.75%vs 71.87%).At 72 hours after treatment the improvement in PaO2 , PaCO2 , pH, BNP in the observation group were significantly better than that in the control group , the differ- ence was significant ( P<0.01 ) .Conclusion NIPPV combined with conventional therapy can significantly improve symptoms of patients with acute left ventricular failure ,and save the life of patients .
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