结直肠癌腹膜转移癌的诊治进展

摘要

Great progress has been made in the diagnosis and treatment of peritoneal carcinomatosis(PC) from colorectal cancer( CRC) .Traditionally, PC from CRC had been considered a form of systemic metastasis porten-ding a terminal state of CRC for which only palliative surgery and/or systemic chemotherapy was recommended.How-ever, patients with metastasis localized to the peritoneum have been shown to be candidates for metastasectomy with improved clinical outcomes.Complete cytoreduction in combination with HIPEC for peritoneal surface disease has been demonstrated to grealtly improve the survival outcomes.This review will examine recent evidence pertaining to the evolving surgical oncology paradigm for management of colorectal peritoneal carcinomatosis.%结直肠癌腹膜转移癌（ CRC PC）的诊断和治疗已经取得很大进展。过去CRC PC被认为是肿瘤晚期并全身转移的表现，一般只行姑息治疗，预后差；如今适当的CRC PC患者经过积极的治疗可显著改善预后。肿瘤细胞减灭术（ CRS）＋腹腔热灌注化疗（ HIPEC）已成为治疗CRC PC的有效手段。该文综述近年来CRC PC的诊治进展。