干燥综合征腮腺导管MRS与CT及X线造影对比研究

摘要

Objective To compare the effect and value between magnetic resonance sialography (MRS),CT siaglography and X-ray sialography in the diagnosis of Sj ögren′s syndrome .Methods Three hundreds and one sus-pected Sjögren′s syndrome,of them 65 cases took MRS,130 cases took CT sialography and 106took X -ray sialogra-phy.And these results were compared .Results These three methods′sensitivity, specificity and Youden index were as following:MRS:95%, 80%, 0.75 , CT sialography:87.5%, 80%, 0.675 , X-ray sialography: 72%, 90%, 0.62 respectively .The area under the ROC curve of MRS , CT sialography and X-ray sialography were 0.875 ,0.837 , 0.815 respectively.Conclusion MRS′s accuracy in the diagnosis of Sj ögren′s syndrome is higher than the conven-tional X-ray sialography, and it is noninvasive and has high clinical value .%目的：对比腮腺导管磁共振水成像（ MRS）、CT造影与X线造影在诊断干燥综合征（ SS）中的作用和价值。方法收集2011－01～2014－01共301例临床疑诊为 SS患者的影像学检查资料，其中行磁共振水成像有65例，行CT造影有130例，行X线造影有106例。将磁共振、CT结果与X线腮腺导管造影结果进行对比研究，评价磁共振腮腺导管水成像诊断干燥综合症的应用价值。结果三种检查方法的敏感度、特异度、Youden指数分别为腮腺导管MRS 95％、80％、0．75，CT造影87．5％、80％、0．675，X线造影72％、90％、0．62。腮腺导管MRS、CT造影及X线造影的ROC曲线下面积分别为0．875、0．837、0．815。结论 SS腮腺导管MRS准确性高于传统X线造影，且为无创性检查，具有较高的临床应用价值。