目的 探讨新生儿先天性十二指肠隔膜症的临床表现、诊断方法及治疗.方法 回顾性分析2010年9月至2013年9月我院新生儿科收治的十二指肠隔膜症新生儿病例资料,总结临床特点及诊治情况.结果 13例先天性十二指肠隔膜症的新生儿住院期间均表现为喂养困难、呕吐明显,多伴有胆汁性呕吐,其中8例通过上消化道造影诊断,3例为先天性肠旋转不良手术中发现诊断,2例通过纤维胃镜检查确诊,平均确诊日龄为14.5天,最迟诊断日龄为41天.11例通过手术治疗治愈出院,1例自动出院,1例合并新生儿坏死性小肠结肠炎放弃抢救死亡.结论 先天性十二指肠隔膜症可能是新生儿喂养困难的重要原因之一,上消化道造影及胃镜在诊断中有重要意义,手术是治疗十二指肠隔膜症的有效方法.%Objective To study the clinical manifestation,diagnostic method and treatment of congenital duodenal diaphragm in neonates.Methods A retrospective study of 13 neonates with congenital duodenal diaphragm admitted to the Department of Neonatology from September 2009 to September 2012 were done.Results The clinical manifestation included feeding intolerance and vomiting grossly with bilious content,8 cases were diagnosed with upper gastrointestinal radiography,3 cases were diagnosed during the operation for congenital intestinal malrotation,and 2 cases were diagnosed with fibrogastroscopy.It took an average of 14.5 days (41 days was the longest)to arrive at the diagnosis.1 l neonates-recovered with surgical treatment,one had treatment withdrawn,and one neonate developed necrotizing enterocolitis (NEC) and died.Conclusions Congenital duodenal diaphragm may be an important cause of neonatal feeding intolerance.Upper gastrointestinal radiography and endoscopy play an important role in the diagnosis of duodenal diaphragm.Surgery is an effective method for the treatment of duodenal diaphragm.
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