糖尿病周围神经病变相关因素研究

摘要

目的:探讨糖尿病周围神经病变(DPN)的相关发病因素.方法:回顾我院2006年1月～2012年2月期间收治的86例糖尿病患者的临床资料,所有患者均做空腹血糖(FPG)、餐后2h血糖(PBG)、总胆固醇(TC)、甘油三脂(TG)、空腹胰岛素(FINS)、餐后2h胰岛素(2hINS)、空腹C肽(FCP)、餐后2hC肽(2hCP)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)检查.结果:通过检查分析,病程、FPG、2hINS、FCP、2hCP、PBG、TG都有明显差异(P<0.05),TC、HDL、LDL差异不明显(P>0.05),62例T1DM患者中出现28例DPN,24例T2DM糖尿病患者中出现7例DPN.结论:DPN的影响因素较多,年龄、病程是DPN的主要危险因素,较好的血糖控制,可以有效预防DPN的发生.%Objective:To study the diabetic peripheral neuropathy (DPN) of the related factors.Methods:To review 86 cases treated patients with diabetes, all of the patients do fasting plasma glucose (FPG), after eating 2 h blood sugar (PBG), total cholesterol (TC), triglycerides (TG), fasting insulin (FINS), after eating 2 h insulin (2 hINS), fasting C peptide (FCP), after eating 2 hC peptide (2 hCP), high-density lipoprotein (HDL), low density lipoprotein (LDL) examination.Results:Through the inspection analysis, duration, and 2 hINS FPG, FCP, 2 hCP, PBG, TG has obvious difference (P<0.05), TC, HDL, LDL no obvious difference (P>0.05), 62 cases of patients with T1DM appeared in 28 patients DPN, 24 cases of T2DM patients with diabetes in 7 cases appear DPN.Conclusion:The influence factors of DPN more, age, duration is a major risk factor for DPN, good blood glucose control, can effectively prevent the occurrence of DPN.