基于磁感相位移谱的脑出血检测中S11和S21的研究

摘要

Cerebral hemorrhage is usually detected by computed tomography,magnetic resonance imaging and positron emission tomography.However,these detection devices are costly and bulky,and can't do bedside and on-site monitoring.In order to study on more extensive cerebral hemorrhage magnetic induction phase shift and to provide more useful information,the study aims to improve the sensitivity of magnetic induction phase shift spectroscopy (MIPSS) detection system for cerebral hemorrhage in the same frequency and the different frequencies based on the established MIPSS detection system.In the study,a cerebral hemorrhage model with 10 rabbits was established by the injection of autologous blood and the cerebral hemorrhage was detected by utilizing the MIPSS detection method under the feature band.According to the characteristics of cerebral hemorrhage phase shift spectroscopy under the feature band,asuperposition method of S11 and S21 in the same frequency and the different frequencies was designed.The results showed that using MIPSS detection method under feature band,the phase shift obviously increased with the increase of injection volume of autologous blood,which could effectively diagnose the severity of cerebral hemorrhage and significantly improve the detection sensitivity.%通常采用计算机断层成像、磁共振成像、正电子发射断层成像检测脑出血,然而,这些设备都存在耗费大、体积大、不能做床边和现场监测的缺点.为了研究更广泛的脑出血磁感应相位移和提供更多有用信息,本研究在已建立的磁感相位移谱(MIPSS)检测系统的基础上,针对同频和不同频这两种情况对系统进行分别分析,从而提高脑出血MIPSS检测系统的灵敏度.采用基于特征频带MIPSS检测方法,对通过自体血注入法建立脑出血的10只家兔进行实验研究,然后根据特征频带下脑出血MIPSS的特点,设计出相同频率和不同频率下S11和S21的叠加方法.结果显示特征频带内兔脑相位差随出血量增加而增大,可以有效地判别脑出血的严重程度,大幅度提高检测灵敏度.