女性正常子宫内膜及卵巢对18F-FDG的生理性摄取特点

摘要

Objective To observe the physiological 18F-FDG uptake of normal endometrium and ovaries in womer.Methods A total of 107 women were examined using whole-body 18 F-FDG PET/CT and were divided into postmenopausal group (n= 29) and premenopausal group (n= 78). All 18 F-FDG PET/CT images were visually interpreted, the SUVmax and the maximum diameter of ovaries (Tmax) were measured. Physiological 18 F-FDG uptake was confirmed according to menstrual history, ultrasonic and CT imaging. Results No physiological 18F-FDG uptake was observed in the endometrium and ovaries in postmenopausal group. In premenopausal group, physiological 18F-FDG uptake of endometrium was observed in 25 subjects, most in ovulatory period and menstrual period, including 10 in ovulatory period with the mean SUVmax of 4.0 ±0. 6, 8 in menstrual period with the mean SUVmax of 5. 1±0. 9. The uptake of ovaries was observed in 35 subjects, including 28 in ovulatory period with the mean SUVmax of 4. 2±0. 8. Tmax of the left and right ovary was (2. 4±0. 7)cm and (2.5±0. 5)cm, respectively. Conclusion In postmenopausal women, no physiological 18F-FDG uptake is observed in the endometrium or ovaries. The physiological uptake of 18 F-FDG in endometrium and ovaries has some characteristics in each level of menstrual cycle.%目的 观察女性正常子宫内膜及卵巢18F-FDG生理性摄取特点.方法 收集107名经临床、B超、CT及随访证实为子宫内膜、卵巢18F-FDG生理性摄取的女性受检者的PET/CT显像资料.按照是否绝经分为绝经组(29名)及未绝经组(78名).应用目测法及半定量分析法分析PET/CT图像特征,测量ROI最大标准摄取值(SUVmax)与卵巢最大直径(Tmax).结果绝经组无子宫内膜及卵巢生理性摄取.未绝经组25名存在子宫内膜生理性摄取,多在排卵期及月经期,其中排卵期10名,平均SUVmax为4.0±0.6;月经期8名,平均SUVmax为5.1±0.9;35名有卵巢生理性摄取,排卵期多见,有28名,平均SUVmax为4.2±0.8.左侧卵巢Tmax为(2.4±0.7)cm,右侧为(2.5±0.5)cm.结论 已绝经女性无子宫内膜及卵巢生理性摄取;未绝经女性在月经周期各阶段子宫内膜及卵巢生理性摄取各具特点.