二维斑点追踪分析肥厚型心肌病患者左心室前壁面只应变

摘要

目的 运用二维斑点追踪成像(STI)技术观察肥厚型心肌病(HCM)患者左心室前壁额断面心肌的面积应变.方法 收集25例肥厚型心肌病患者(HCM组)及25名健康志愿者(对照组),应用STI技术在左心室前壁心肌额断面采集25个ROI的面积应变,获得收缩期应变(ε)、收缩期应变率(SRS),舒张早期应变率(SRE)、舒张晚期应变率(SRA)；比较两组的差异,并分析其与各左心室功能参数的相关性.结果 HCM组ε、SRS及SRE均低于对照组,而SRA高于对照组(P均＜0.01)；ε、SRS、SRE、SRA与左心室相对室壁厚度(RWT)、左心室质量指数(LVMI)呈线性负相关关系(P均＜0.01).结论 STI技术能够用于观察左心室前壁额断面心肌的面积应变,检出HCM患者的左心室局部心肌功能异常.%Objective To observe the myocardial area strain at the anterior wall (AW) of left ventricle (LV) in hypertrophic cardiomyopathy (HCM) patients with two-dimensional speckle-tracking imaging (STI).Methods Twenty-five HCM patients (HCM group) and 25 healthy subjects (control group) were collected.Twenty-five ROIs on the AW of LV were tracked by STI.The strain (ε),strain rates in systole (SRS),strain rates in early-diastole (SRE),strain rates in late-diastole (SRA) on 25 ROIs were collected,and the mean valued of 25 ROIs were compared between the two groups.The correlation between the parameters of STI and left ventricular function were analyzed.Results Compared with the control group,e,SRS and SRE significantly decreased,but SRA increased in HCM group (all P＜0.01).There were negative correlations between parameters of STI and left ventricular relative wall thickness and left ventricular mass index,respectively (all P＜0.01).Conclusion STI can be used for observing the myocardial area strain at AW to detect the abnormal myocardial of LV in patients with HCM.