超声微泡造影剂携基因抑制肾间质纤维化的研究进展

摘要

With the improving of preparing technology of ultrasound microbubbles and the understanding of mechanism of renal fibrosis, ultrasound-microbubble-mediated gene therapy of renal fibrosis has got some success. Compared with other gene transfection, this method is more efficient and safe. In this article, the development of ultrasound microbubbles carrying genes for resist renal interstitial fibrosis were reviewed.%随着超声微泡造影剂制备技术的提高,以及对肾间质纤维化分子机制的进一步深入研究,微泡介导基因抑制肾间质纤维化已取得了一定成效,且比其他基因转染方法更为高效和安全.本文就超声微泡携相关基因抗肾间质纤维化的研究进展进行综述.