ReCell(R)技术治疗稳定性白癜风的临床疗效

摘要

Objective To evaluate the preliminary outcome of stable vitiligo treatment with ReCell(R )technique.Methods Six patients with stable vitiligo were treated with ReCell(R ) technique.In each patient,a thin razor-thickness cutaneous biopsy was harvested from uninvolved area near the vitiligo patches.It was then processed through the ReCell(R ) system and 1 ml autologous epidermal cell suspension was obtained.The lesion area was dermabraded using a diamond fraise wheel to the dermoepidermal junction.The cell suspension was then sprayed on the wound and covered with non-adhering dressings.Results The patients were followed up for 6 months.5 patients presented with repigmentaion in the treated area.There was no significant response in one patient who was diagnosed as systematic vitiligo.Conclusions The ReCell(R ) technique is an alternative treatment for stable vitiligo patients.The clinical outcome will be satisfactory when appropriate patients are selected.%目的 探索ReCell(R )技术治疗稳定性白癜风患者的疗效.方法 对6例白癜风患者应用ReCell(R )技术治疗,于病变外围切取少量厚度为0.2 mm的刃厚皮片,将其置入ReCell(R ))试剂盒内酶解后,形成表皮细胞悬液.病变部位应用微型动力系统磨削后,创面喷洒制备的表皮细胞悬液,加压包扎.结果 平均随访6个月.5例寻常型白癜风患者出现不同程度的色素恢复,色素恢复面积均＞50％.1例泛发型白癜风患者治疗无效.结论 ReCell(R )技术是治疗白癜风的有效外科方法之一.为了获得良好的治疗效果,适应证的选择非常关键.