A TECHNIQUE TO ENHANCE THE CLINICAL EFFICIENCY OF RADIOTHERAPY AND RADIOSURGERY USING PERTURBATIVE BEAMING AND TISSUE-SPECIFIC RADIOBIOLOGY

摘要

This invention relates to a technique to enhance the clinical efficiency of radiotherapy and radiosurgery using perturbative beaming and tissue specific radiobiology, comprising, considering the normal steady beam dose rate, then increasing the temporal stochastic fluctuation of the output intensity of the radiation beam from a medical linear accelerator or cobalt gamma knife beam setup, developing a computer-based methodology by considering the tumor specific radiobiology and magnitude of the tailor made dose rate fluctuation using an embedded system device consisting of requisite hardware and software as described herein.