乳腺癌MRI的特征性表现与腋窝淋巴结转移的相关性分析

摘要

Objective: To explore the relationship between the characteristic of breast cancer MRI and axillary lymph node metastasis, thus offering therapeutic schedule and prognosis in treating breast cancer.Materials and Methods:Forty-four cases of breast cancer were conifrmed by pathology and preoperative MR scan, twenty-six cases of these patients were conifrmed with ipsilateral axillary lymph node metastasis. Two experts read MRI image, and analyze the relationship between the ratio of different masses' short axis over long axis, dynamic enhanced MR features and the axillary lymph node metastasis of breast cancer.Results:(1) MR morphology analysis shows that the ratio of breast lumps' short axis over long axis has a negaive correlation with axillary lymphnode matastasis (t=5.892,P<0.05). (2) Edge reinforcement tumors' early intensive rate of breast cancer has positive correlation with axillary lymph node metastasis (t=3.966,P<0.01).Conclusion:The larger the ratio of breast lumps' short axis over long axis is, the smaller the possibility of axillary lymph node metastasis will be, the bigger edge reinforcement tumors' early intensive rate is, the greater the possibility of lymph node metastasis will be, and associated with poor prognosis. Therefore, axillary lymph node metastasis of breast cancer has good correlation with MR characteristic. MR examination can judge prognosis of breast cancer and axillary lymph node properties, then provide reference for effective treatment.%目的：探讨乳腺癌MRI的特征性表现与腋窝淋巴结转移的相关性，为乳腺癌淋巴结阳性患者治疗方案的选择及预后评估提供理论依据。材料与方法44例经病理证实为乳腺癌且均术前行MR扫描，其中26例患者证实有同侧腋窝淋巴结转移。由2名有经验的影像科医师阅读MRI，分析不同肿块的短径与长径之比、动态增强的特征与乳腺癌腋窝淋巴结转移的相关性。结果(1)MR形态学分析乳腺肿块短径和长径之比与腋窝淋巴结转移呈负相关性(t=5.892， P＜0.05)；(2)早期边缘强化率与腋窝淋巴结转移呈正相关性(t=3.966， P＜0.01)。结论乳腺癌肿块短径及长径之比越大，其腋窝淋巴结转移可能性越小，肿块早期边缘强化率越大，淋巴结转移可能性越大，且提示预后不良。可见，乳腺癌腋窝淋巴结转移与MR的特征具有较好的相关性，MR检查可对判断乳腺癌预后和腋窝淋巴结性质制定有效治疗方案提供参考。