LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH NORMAL CORONARY ANGIOGRAM BUT POSITIVE TREADMILL TEST

摘要

To investigate the relationship between left ventricularmass index(LVMI),left ventricular end-diastolic volume(EDV)andmyocardial ischemia induced with treadmill exercise test in patientswith normal coronary angiogram.Method:Sixty-one male patientswith normal coronary angiogram were divided into two groupsaccording to treadmill test:positive(23 cases)and negative group(38 cases).Left ventricular end-diastolic diameter(EDD),interventricular septum thickness(IVST),posterior wall thickness(PWT),EDV,LVMI,etc.were measured or calculated withechocardiography.Results:LVMI in positive treadmill test group(114.2±35.8 g/m^2)was markedly larger than that in negative group(90.7±16.1,p=0.0009).IVST and PWT in positive group weresignificantly thicker than those in negative group(p=0.00002,0.00003).EDD and EDV were not different between the groups.Conclusions:The left ventricular mass increased markedly inpatients with normal coronary angiogram but positive treadmillexercise test.Left ventricular hypertrophy or hypertrophy-relatedchanges,e.g.reduction of coronary reserve,may be the cause ofischemia at exercise.The end-diastolic size of left ventricle was notrelated to ischemia induced by exercise in patients with normalcoronary angiogram.