复方调脂降糖汤治疗糖尿病代谢综合征的临床观察

摘要

Objective To observe the effects of compound Tiaozhi Jiangtang decoction (Co- TZJT) on metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM). Methods One hundred and thirty- four patients (pts) with MS and T2DM were randomly assigned to two groups:Control group (n= 67) treated with routine therapy and treatment group (n= 67) treated with Co - TZJT and routine therapy. Fasting blood glucose (FBG), blood lipid (BL), insulin, glycosylated hemoglobin( H bAIC ), weight and waist circumference were checked at the end of 4th and 8th week. Results The FBG,blood lipid,insulin,and HbAIC were improved in Co-TZTT group. Conclusion Co- TZJT could improve insulin resistance and reduce harmful factors of MS.%目的 观察复方调脂降搪汤治疗2型糖尿病(T2DM)代谢综合征(MS)的临床疗效.方法 将符合入选标准的134例以2型糖尿病代谢综合征患者分为治疗组(67例)和对照组(67例).对照组常规给予降糖、降压药物,使血糖、血压达到稳定且符合入组条件,治疗组在对照组用药基础上给予复方调脂降糖汤口服.检测两组治疗前及治疗4周,8周后空腹血糖、血脂、血清胰岛素、糖化血红蛋白、腰围和减轻体重等指标.结果 两组治疗8周后,在三酰甘油、高密度脂蛋白、体重、空腹血糖、空腹胰岛素、胰岛素抵抗指数、腰围等指标较治疗前有明显改善(P<0.05).其中治疗组低密度脂蛋白、体重、空腹胰岛素、胰岛素抵抗指数等指标优于对照组(P<0.05).结论 复方调脂降糖汤具有明显改善胰岛素抵抗作用,同时可以降糖、调脂、减小腰围和体重,缓解MS的多种危害因素.