补气通络方治疗气虚痰瘀阻络型脑梗死恢复期的临床疗效研究

摘要

Objective To investigate the effect of Buqi Tongluo prescription (BTP) in the treatment of cerebral intarction at convalescence with qi deficiency and phlegm and blood stasis syndrome.Methods Sixty patients with cerebral infarction at convalescence with qi deficiency and phlegm and blood stasis syndrome were randomly divided into two groups:control group (n =30) treated with routine treatment,and treatment group (n =30) treated with BTP in the basis of routine treatment for 2 months.The clinical effect was evaluated after a course.The changes of blood rheology,nerve function defect score and Barthel indexe before and after treatment were observed.Results The total clinical effective rate was 86.67％ in treatment group,which was significantly higher than that in control group (63.33％,P ＜0.05).There was significant difference in blood rheology,nerve function defect and Barthel indexe between two groups before and after treatment (P ＜0.05).The changes in treatment group was more obvious than that in control group (P ＜0.05).Conclusion BTP can effectively improve blood rheology,nerve function defect,and activities of daily living,promote the recovery in patients with cerebral infarction at convalescence with qi deficiency and phlegm and blood stasis syndrome.%目的 观察补气通络方治疗气虚痰瘀阻络型脑梗死恢复期的临床疗效及其对血液流变学指标的影响.方法 将60例气虚痰瘀阻络型脑梗死恢复期病人随机分为两组.对照组30例,予西医常规治疗;治疗组30例,在对照组治疗的基础上加用补气通络方口服.两组均治疗2个月为1个疗程,1个疗程后评定临床疗效,观察两组治疗前后血液流变学指标及神经功能缺损评分和日常生活能力(Barthel)指数评分变化.结果 治疗组总有效率86.67％,对照组总有效率63.33％,治疗组疗效优于对照组(P＜0.05).两组治疗后神经功能缺损评分及Barthel指数均较前改善,治疗组治疗后改善程度较对照组更为显著(P＜0.05);治疗组治疗后血液流变学指标显著低于治疗前及对照组并具有统计学意义.结论 补气通络方能有效改善气虚痰瘀阻络型脑梗死恢复期病人的血液流变学、神经功能缺损评分和日常生活能力指数评分等指标,促进病人神经功能康复,提高日常生活能力,且安全无毒副作用.