Objective:To investigate the clinically curative effects of Liyuan Pure Lysothrombusase(LYPL，力源精纯溶栓酶) on unstable angina pectoris (UAP) and to observe its safety.Methods:One hundred and twenty cases with UAP were selected and in accordance with the proportion of one to one randomly divided into treated and control group.Based on conventional therapy the LYPL infused intravenously was added in treated group.The conditions of symptomatic convalescence,the changes in electrocardiography (ECG),and the parameters of blood rheology were observed for two groups.Results:The curative effects on symptoms and ECG were 93.33％ and 88.33％ respectively in treated group but in control group they were 70.00％ and 68.33％ respectively.The difference in comparison between two groups was significant (all P<0.01).In treated group the parameters of blood rheology were obviously improved meanwhile in control group they were not.Conclusions:LYPL possesses the actions on improving blood rheology.Its curative effects on UAP are marked and it is safe and easy to use.%目的：探讨力源精纯溶栓酶治疗不稳定型心绞痛（UAP）的临床疗效及安全性观察。方法：选择120例UAP患者，依照随机分组方法，按1∶1比例分成治疗组和对照组，治疗组在内科常规治疗的基础上加用力源精纯溶栓酶静滴。观察2组患者症状缓解情况、心电图变化和血液流变性指标。结果：治疗组心绞痛疗效，心电图疗效分别为93.33%和88.33%，对照组分别为70.00%和68.33%，有显著性差异（P均<0.01）；治疗组血液流变学指标有明显改善，而对照组改善不明显。结论：力源精纯溶栓酶具有改善UAP血液流变学特性的作用，疗效显著，使用方便、安全
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