目的 观察芪蛭通络胶囊对气虚血瘀型中风后遗症患者的治疗作用.方法 选取 2014年10月至2017年10月广西壮族自治区民族医院中医科收治的气虚血瘀型中风后遗症患者74例,按随机数字表法分为对照组(36例)和观察组(38例).两组均静脉滴注(静滴)血塞通并给予针灸治疗,保持饮食清淡.对照组加用补阳还五汤(黄芪50 g、当归尾12 g、地龙10 g、桃仁10 g、川芎10 g、红花8 g、赤芍10 g),每日1剂,分早晚2次煎服,连用2个月;观察组加用芪蛭通络胶囊2 g,每日2次,连用2个月.比较两组神经功能缺损评分(NDS)和血脂指标三酰甘油(TG)及胆固醇水平的差异,并观察两组临床疗效.结果 观察组和对照组治疗前NDS评分(分:26.2±3.5比26.5±3.4)、TG(mmol/L:3.7±0.4比3.8±0.3)、胆固醇(mmol/L:7.5±1.3比7.3±1.2)水平比较差异均无统计学意义(均P>0.05),治疗后上述指标均较治疗前显著降低,且以观察组治疗后的降低程度较对照组更显著〔NDS评分(分):12.6±2.8比20.7±2.8,TG(mmol/L):1.1±0.2比1.9±0.3,胆固醇(mmol/L):4.8±1.2比5.7±1.1,均P<0.05〕;观察组总有效率明显高于对照组〔94.7%(36/38)比80.6%(29/36),P<0.05〕.结论 芪蛭通络胶囊治疗气虚血瘀型中风后遗症具有提高临床疗效、有效减轻患者神经功能缺损程度的作用.%Objective To observe the therapeutic effect of Qizhi Tongluo capsule on patients with apoplexy sequelae accompanied by qi deficiency and blood stasis. Methods Seventy-four patients with apoplexy sequelae accompanied by qi deficiency and blood stasis syndrome admitted to the Department of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region National Hospital From October 2014 to October 2017 were enrolled, they were randomly divided into a control group (36 cases) and an observation group (38 cases). Both groups were treated with acupuncture and moxibustion, intravenous drip of Xuesaitong and kept on a diet light, in control group, additionally Buyang Huanwu decoction (the ingredients: astragalus 50 g, angelica sinensis 12 g, allolobophora caliginosa trapezoides 10 g, peach kernel 10 g, szechwan lovage Rhizome 10 g, safflower 8 g, radix paeoniae rubra 10 g) was given, 1 dose daily, 1/2 dose being orally taken in the morning and 1/2 dose in the evening for consecutive 2 months: in the observation group, Qizhi Tongluo capsule 2 g was added, 2 times a day for consecutive 2 months. The differences in nerve function deficit score (NDS), the levels of triglyceride (TG) and cholesterol levels between the two groups were compared, and clinical therapeutic effects of two groups were observed. Results There were no statistical significant differences in NDS score (26.2±3.5 vs. 26.5±3.4), TG (mmol/L: 3.7±0.4 vs. 3.8±0.3), cholesterol (mmol/L: 7.5±1.3 vs. 7.3±1.2) before treatment in both groups (all P > 0.05), after treatment, the above indexes were significantly lowered than those before treatment, and the degrees of decrease after treatment in the observation group were more significant than those in the control group [NDS score: 12.6±2.8 vs. 20.7±2.8, TG (mmol/L): 1.1±0.2 vs. 1.9±0.3, cholesterol (mmol/L):4.8±1.2 vs. 5.7±1.1, all P < 0.05]; the total therapeutic effective rate in the observation group was significantly higher than that in the control group [94.7% (36/38) vs. 80.6% (29/36), P < 0.05]. Conclusion Qizhi Tongluo capsule can improve the clinical efficacy and effectively reduce the degree of nerve function defect in patients with apoplectic sequelae accompanied by qi deficiency and blood stasis syndrome.
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